
Chemistry Letters p. 1873 - 1876 (1993)
Update date:2022-08-03
Topics:
Kurome, Toru
Inami, Kaoru
Inoue, Tetsuya
Ikai, Katsushige
Takesako, Kazutoh
et al.
A total synthesis of an antifungal cyclic depsipeptide aureobasidin A was first achieved mainly using PyBroP as a coupling reagent.The synthetic cyclized product was completely identical with the natural antibiotic in all respects.Some unexpected reactions due to N-methylamino acid were also described.
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(1970)