β-Lithiations of carboxamides. Synthesis of β-substituted-α,β- unsaturated amides

DOI: 10.1002/jhet.5570300515

Source and publish data:

Journal of Heterocyclic Chemistry p. 1261 - 1265 (1993)

Update date:2022-07-29

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Authors:

Katritzky

Szajda Szajda

Lam Lam

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Article abstract of DOI:10.1002/jhet.5570300515

N-Methyl-2-methyl-3-(benzotriazol-1-yl)propanamide, on treatment with butyllithium forms a dianion which on treatment with alkyl and benzyl halides, aldehydes and ketones affords monosubstituted products; with ethyl p-toluate, a lactam is formed. The alky

Full text of DOI:10.1002/jhet.5570300515

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