Journal of the American Chemical Society p. 2348 - 2355 (1994)
Update date:2022-09-26
Topics:
Robl, Jeffrey A.
Cimarusti, Maria P.
Simpkins, Ligaya M.
Weller, Harold N.
Pan, Yolanda Y.
Malley, Mary
DiMarco, John D.
New methodology for the synthesis of substituted seven-membered lactams 3 has been developed. This method allows for the stereoselective introduction of substituents at the C-7 position of the azepinone ring as well as α to the acetic acid side chain. Deh
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