Halogen atom transfer radical cyclization of N-allyl-N-benzyl-2,2-dihaloamides to 2-pyrrolidinones, promoted by Fe0-FeCl3 or CuCl-TMEDA

DOI: 10.1016/S0040-4020(97)00908-3

Source and publish data:

Tetrahedron p. 14031 - 14042 (1997)

Update date:2022-08-05

Topics:

Authors:

Benedetti, Miriam

Forti, Luca

Ghelfi, Franco

Pagnoni, Ugo Maria

Ronzoni, Roberto

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00908-3

The halogen atom transfer radical cyclization of a N-allyl-N-benzyl-2,2-dihaloamides to 2-pyrrolidinones has been carried out in high yields under mild conditions, in a reaction promoted by CuCl-TMEDA or Fe⁰-FeCl₃ in acetonitrile or N,N-dimethylformamide, respectively.

Full text of DOI:10.1016/S0040-4020(97)00908-3

Products guided by the article

Product name:2,2-Dichloro-3-phenyl-propionyl chloride

Cas No:155088-11-2

R&D Labs maybe for 155088-11-2

Jintan Jinnuo Chemical Co., Ltd.

Contact:+86-519-80199901

Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
SINFACHEM LIMITED

Contact:86-25-84683399

Address:605, Phoenix Herui Plaza, No.389, South Taiping Road, Nanjing, China 210002
shandong zhongke taidou chemical co.,ltd

Contact:86-531-88682301

Address:Jinan shandong Province CHina
ZCIC INTERNATIONAL LTD

Contact:+86-512-56795332

Address:No227 Shuanglong Rd, Fenghuang, Zhangjiagang
GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.

Relevant to this article

Isolation, Structure, and Synthesis of Dolastatin C, a New Depsipeptide from the Sea Hare Dolabella auricularia

Doi:10.1016/S0040-4039(00)61355-2
(1993)
Base-Induced Photocyclization of 1,2-Diaryl-1-tosylethenes. A Mechanistically Novel Approach to Phenanthrenes and Phenanthrenoids

Doi:10.1021/ol0357954
(2003)
Organocatalyzed synthesis of (-)-4-epi-fagomine and the corresponding pipecolic acids

Doi:10.1016/j.tet.2015.07.036
(2015)
Synthesis of carba-strigol analogues

Doi:10.1002/recl.19941130103
(1994)
Design, synthesis and biological evaluation of novel thiosemicarbazone-indole derivatives targeting prostate cancer cells

Doi:10.1016/j.ejmech.2020.112970
(2021)
Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C₁-C₈ δ-lactone subunit

Doi:10.1039/c39930001790
(1993)

Article Doi