Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C1-C8 δ-lactone subunit

DOI: 10.1039/c39930001790

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Journal of the Chemical Society. Chemical communications p. 1790 - 1792 (1993)

Update date:2022-08-05

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Authors:

Paterson

Wren Wren

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Article abstract of DOI:10.1039/c39930001790

The stereoselective, boron-meditated, aldol/reduction sequence, 4+5→8→9, allows an efficient asymmetric synthesis of the σ-lactone-containing, C₁-C₈ subunit of discodermolide.

Full text of DOI:10.1039/c39930001790

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