Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C1-C8 δ-lactone subunit

DOI: 10.1039/c39930001790

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1790 - 1792 (1993)

Update date:2022-08-05

Topics:

Authors:

Paterson

Wren Wren

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39930001790

The stereoselective, boron-meditated, aldol/reduction sequence, 4+5→8→9, allows an efficient asymmetric synthesis of the σ-lactone-containing, C₁-C₈ subunit of discodermolide.

Full text of DOI:10.1039/c39930001790

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(E)-(2R,3S,4R,5R,7R)-1-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-dec-8-ene-3,5-diol

Cas No:155649-74-4

R&D Labs maybe for 155649-74-4

Xi'an North Information Industry Co., Ltd. Weilv Chemical Department

Contact:+86-29-88156413

Address:Jixiang Road 99 Xi'an Shaanxi Province
Jiangsu Feymer Technology Co., Ltd.

Contact:+86-512-58110132

Address:Fenghuang Town, Zhangjiagang City, Jiangsu Province, China
Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Zhongshan Haihong Medicine Co., Ltd.

Contact:86-0760-86925778 （0）18824993998

Address:A7 building,lianyuan road Torch Hi-tech Industrial Development Zone
Pure Chemistry Scientific Inc.

Contact:+1-857-366-7588

Address:14905 SW freeway street #232, Sugarland, TX 77478, USA

Relevant to this article

Mononuclear (allenylidene)metal complexes of a d⁸ system: Synthesis and molecular structure of trans-[RhCl(=C=C=CRR′)(PiPr₃)₂]

Doi:10.1021/om00019a031
(1994)
Ferrocenyl-phosphonium ionic liquids-synthesis, characterisation and electrochemistry

Doi:10.1039/c3dt53402b
(2014)
Palladium-catalyzed intramolecular hydroamination of propargylic carbamates and carbamothioates

Doi:10.1021/ol5002279
(2014)
(-)-(4S,5R)-4-(2-pyridyl)-5-(diphenylphosphino)methyl-2,2-dimethyl-1,3 -dioxolane a new chiral ligand for enantioselective catalysis

Doi:10.1016/S0957-4166(00)86190-X
(1994)
Enantioselective oxidative-coupling of polycyclic phenols

Doi:10.1016/j.tet.2014.01.017
(2014)
Synthesis and Self Association of 4,7-Diamino-2,9-dimethyl-5,6,11a-triaza-6,11,11a,12-tetrahydronaphthacene Derivatives as Dibenzoguanidine Receptors for Oxoanion Recognition

Doi:10.1039/c39940001193
(1994)

Article Doi