
Tetrahedron p. 3327 - 3332 (1994)
Update date:2022-08-04
Topics:
Adam, Solange
The quinuclidinyl analogue 1 related to the potent antimalarial agent mefloquine has been synthesised in a stereospecific way resting on the E geometry of the key step olefin 9 obtained via the Heck's palladium-catalysed vinylic substitution reaction.
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Doi:10.1016/j.tetlet.2014.01.019
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