Palladium-Catalyzed Heteroarylation of 1-(tert-Butyldimethylsilyl)-3-indolylzinc Chloride. Efficient Synthesis of 3-(2-Pyridyl)indoles

DOI: 10.1016/S0040-4039(00)75819-9

Source and publish data:

Tetrahedron Letters p. 793 - 796 (1994)

Update date:2022-08-05

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Authors:

Amat, Mercedes

Hadida, Sabine

Bosch, Joan

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Article abstract of DOI:10.1016/S0040-4039(00)75819-9

Palladium-catalyzed coupling of 1-(tert-butyldimethylsilyl)-3-indolylzinc chloride (2) with either ?-deficient or ?-excedent heteroaryl halides gives 3-arylindoles in good to excellent yields.The method is extensively applied to the preparation of 3-(2-pyridyl)indoles.

Full text of DOI:10.1016/S0040-4039(00)75819-9

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