Journal of the Chemical Society. Chemical communications p. 455 - 456 (1994)
Update date:2022-07-29
Topics:
Yuasa, Yoko
Ando, Jun
Shibuya, Shiroshi
A new and highly enantioselective synthesis of trans 5-substituted 2-hydroxymethylpyrrolidine derivatives is achieved by intramolecular radical cyclization at the 4-position of Δ4,5-oxazolidin-2-one, which leads to C2-symmetrical 2,5-dibenzyloxypyrrolidin-2-one.
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