Synthesis of enantiopure piperidines. Total synthesis of (2R,6S)-2-methyl-6-propylpiperidine [(-)-dihydropinidine]

DOI: 10.1016/0957-4166(96)00096-1

Source and publish data:

Tetrahedron Asymmetry p. 977 - 980 (1996)

Update date:2022-08-05

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Authors:

Amat, Mercedes

Llor, Nuria

Hidalgo, Jose

Hernandez, Albert

Bosch, Joan

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Article abstract of DOI:10.1016/0957-4166(96)00096-1

Enantiomerically pure 2-alkyl-, 3-alkyl-, 4-alkyl-, and cis-2,6-dialkylpiperidines are prepared from the chiral, non-racemic oxazolopiperidone 1. An asymmetric synthesis of (2R,6S)-(-)-dihydropinidine is reported.

Full text of DOI:10.1016/0957-4166(96)00096-1

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Product name:(1'R,3S)-(-)-1-(2'-hydroxy-1'-phenylethyl)-3-methylpiperidin-2-one

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