Journal of Organic Chemistry p. 2423 - 2429 (1994)
Update date:2022-08-05
Topics:
Pirrung, Michael C.
Han, Hyunsoo
Nunn, David S.
Mechanistic studies of isopropylmalate dehydrogenase (IMDH, EC 1.1.1.85), the penultimate enzyme in leucine biosynthesis in bacteria and yeast, have been conducted.It performs two chemical operations, oxidation and decarboxylation, on isopropylmalate to p
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