Synthesis and biological activity of the novel adenosine analogs; 3- amino-6-(β-D-ribofuranosyl)pyrazolo[3,4-c]pyrazole and 3-amino-1-methyl-6- (β-D-ribofuranosyl)pyrazolo[3,4-c]pyrazole

Article abstract of DOI:10.1080/15257779408013250

Chemical modification of the 4-nitrile group in 5-amino-1-(2,3,5-tri-O- benzyl-β-D-ribofuranosyl)pyrazole-4-carbonitrile (1) afforded 5-amino-4-(5- methyl-1,2,4-oxadiazol-3-yl)-1-(2,3,5-tri-O-benzyl-β-D- ribofuranosyl)pyrazole (3). The methylation of 3, v

Full text of DOI:10.1080/15257779408013250

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Nucleosides and Nucleotides
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Synthesis and Biological Activity of the
Novel Adenosine Analogs; 3-Amino-6-
(β-D-ribofuranosyl)pyrazolo[3,4-
c]pyrazole and 3-Amino-1-methyl-6-(β-D-
ribofuranosyl)pyrazolo[3,4-c]pyrazole
David A. Berry a b c , Linda L. Wotring a b c , John C. Drach a b c
Leroy B. Townsend a b c
&
a Department of Medicinal Chemistry and Pharmaceutical
Chemistry , College of Pharmacy , Ann Arbor, Michigan, 48109
b Department of Chemistry , College of Literature, Sciences, and
Arts , Ann Arbor, Michigan, 48109
c Department of Biologic and Materials Sciences , School of
Dentistry, The University of Michigan , Ann Arbor, Michigan, 48109
Published online: 23 Sep 2006.
To cite this article: David A. Berry , Linda L. Wotring , John C. Drach & Leroy B. Townsend
(1994) Synthesis and Biological Activity of the Novel Adenosine Analogs; 3-Amino-6-(β-D-
ribofuranosyl)pyrazolo[3,4-c]pyrazole and 3-Amino-1-methyl-6-(β-D-ribofuranosyl)pyrazolo[3,4-
c]pyrazole, Nucleosides and Nucleotides, 13:1-3, 405-420, DOI: 10.1080/15257779408013250
To link to this article: http://dx.doi.org/10.1080/15257779408013250
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