Heterocycles p. 823 - 832 (1994)
Update date:2022-07-29
Topics:
Miyashita, Akira
Sasaki, Takami
Oishi, Etsuo
Higashino, Takeo
The treatment of 4-chloroquinazoline (1) with arylmagnesium bromide (3) in tetrahydrofuran (THF) resulted in the formation of 2-arylmethyleneaminobenzonitrile (2).Continued reaction of ring opening of 1 and subsequent hydrolysis of the products (2) afforded the corresponding arenecarbaldehydes (4).
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Doi:10.1246/bcsj.57.3021
(1984)Doi:10.3390/md8020347
(2010)Doi:10.1016/0223-5234(93)90088-V
(1993)Doi:10.1007/BF02219706
(1996)Doi:10.1039/c3ob42131g
(2014)Doi:10.1021/jo00086a055
(1994)