1,5-Benzodiazepines XI. 5-(Dialkylamino) or 5-(alkylthio) substituted 8-chloro-6-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepines with anticonvulsant activity

DOI: 10.1016/0223-5234(93)90088-V

Source and publish data:

European Journal of Medicinal Chemistry p. 577 - 584 (1993)

Update date:2022-07-29

Topics:

Authors:

Grossi Grossi

Di Braccio

Roma Roma

Ghia Ghia

Brambilla

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Article abstract of DOI:10.1016/0223-5234(93)90088-V

The cyclocondensation of (dimethylamino)benzodiazepinones 3a,b with hydrazides yielded triazolobenzodiazepinones 4 which were treated with Lawesson's reagent to give thiolactams 5. The phase-transfer catalyzed (TEBA) alkylation of compounds 5 with suitabl

Full text of DOI:10.1016/0223-5234(93)90088-V

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Product name:8-chloro-5-morpholin-4-yl-6-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine

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