Nonpeptide Peptidomimetic Antagonists of the Neuropeptide Y Recepyor: Benextramine Analogs with Selectivity for the Peripheral Y2 Receptor

DOI: 10.1021/jm00040a018

Source and publish data:

Journal of Medicinal Chemistry p. 2242 - 2248 (1994)

Update date:2022-08-04

Topics: Antagonist Selectivity Analog Receptor Neuropeptide Y

Authors:

Chaurasia, Chandra

Misse, Gregory

Tessel, Richard

Doughty, Michael B.

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Article abstract of DOI:10.1021/jm00040a018

We synthesized a new series of benextramine analogs as neuropeptide Y (NPY) functional group mimetics and tested them for N-NPY (<3>NPY) displacement activity in rat brain membrane homogenates and for NPY receptor antagonist activity in the

Full text of DOI:10.1021/jm00040a018

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