Synthesis p. 443 - 449 (1997)
Update date:2022-08-03
Topics: Yield Catalyst Solvent Analog Purification Tryptamines Direct synthesis Conformationally restricted Reactant
Macor, John E.
Blank, David H.
Ryan, Kevin
Post, Ronald J.
An efficient, two step synthesis of-(pyrrolidin-3-yl)indoles 4 is described. Indoles react with maleimides in refluxing acetic acid affording 3-(indol-3-yl)succinimides 6. Reaction times and yields depend on the substituents on the indole 5. Direct reduct
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