Na+-glucose cotransporter inhibitors as antidiabetic agents. III. Synthesis and pharmacological properties of 4'-dehydroxyphlorizin derivatives modified at the OH groups of the glucose moiety

DOI: 10.1248/cpb.46.1545

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1545 - 1555 (1998)

Update date:2022-08-03

Topics:

Authors:

Hongu, Mitsuya

Funami, Nobuyuki

Takahashi, Youichi

Saito, Kunio

Arakawa, Kenji

Matsumoto, Mamoru

Yamakita, Hirokazu

Tsujihara, Kenji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.1545

To overcome hydrolysis by β-glucosidase present in the digestive tract, the OH groups on the glucose moiety of the 4'-dehydroxyphlorizin derivatives (1, 2, 3) were modified with various kinds of patterns, and then the effects of the modified compounds on

Full text of DOI:10.1248/cpb.46.1545

NII-Electronic Library Service

Products guided by the article

Product name:6'-benzyloxycarbonyloxy-2'-hydroxy-4-methoxydihydrochalcone 2'-O-(2,3-O-dibenzyloxycarbonyl-β-D-glucopyranoside)

Cas No:156729-34-9

R&D Labs maybe for 156729-34-9

Sdow

website:http://www.sdowchem.com

Contact:86-135-2193 7483

Address:8-106 taiyue building
Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-62886900

Address:Keji Road NO.70
Wuxi Innopal International Trade CO.,LTD

Contact:+86-510-80711901-8003

Address:Room 402,Building 5,Longze Garden,No.17,South huanjiu Road,Yixing City, Jiangsu,China
SPRING CHEMICAL INDUSTRY CO.,LTD

Contact:86-187-66672125

Address:linchi industry park.zouping
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China

Relevant to this article

Synthesis and biological activity of anthelmintic thiadiazoles using an AF-2 receptor binding assay

Doi:10.1016/S0960-894X(99)00267-X
(1999)
Development of novel guanidine-bisurea bifunctional organocatalysts and their application to asymmetric α-hydroxylation of tetralone-derived β-keto esters

Doi:10.1071/CH14144
(2014)
Asymmetric hydrogenation of quinoxalines, benzoxazines, and a benzothiazine catalyzed by chiral ruthenabicyclic complexes

Doi:10.1002/adsc.201300604
(2013)
Pd-catalyzed nucleophilic fluorination of aryl bromides

Doi:10.1021/ja5009739
(2014)
Supramolecular ensemble of PBI derivative and copper nanoparticles: A light harvesting antenna for photocatalytic C(sp²)-H functionalization

Doi:10.1039/c6gc01728b
(2016)
Squaramide equilibrium acidities in DMSO

Doi:10.1021/ol5005017
(2014)

Article Doi