Heterocycles p. 333 - 344 (1994)
Update date:2022-08-02
Topics:
Martinez-Merino, Victor
Gil, Maria J.
Gonzalez, Alberto
Zabalza, Jose M.
Navarro, Javier
Manu, Maria A.
New series of ethyl 5-substituted 2,3-dihydro-3-oxoisothiazolo<5,4-b>pyridine-2-acetate was prepared either a) directly by reaction of 5-substituted 2-chlorothio-3-pyridinecarbonyl chlorides with ethyl glycinate or b) by oxidation of the correspondent 2-mercapto-3-pyridinecarboxamides.New 5-substituted 1,2-dihydro-2-thio-3-pyridinecarboxylic acids as starting materials are described.
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