Guanosine Derivatives Bearing an N2-3-Imidazolepropionic Acid

DOI: 10.1016/S0040-4039(00)76823-7

Source and publish data:

Tetrahedron Letters p. 3045 - 3048 (1994)

Update date:2022-08-03

Topics:

Authors:

Heeb, Norbert V.

Benner, Steven A.

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Article abstract of DOI:10.1016/S0040-4039(00)76823-7

Synthesis of a 2'-deoxyguanosine analog tethered through the exocyclic nitrogen via a 3 carbon chain to the 4-position of an imidazole is described.The imidazole forms a hydrogen bond with the 2'-hydroxyl group of a complementary cytosine bound as a Watson-Crick base pair.

Full text of DOI:10.1016/S0040-4039(00)76823-7

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