Tetrahedron Letters p. 1247 - 1250 (1994)
Update date:2022-08-05
Topics:
Kigoshi, Hideo
Ojika, Makoto
Suenaga, Kiyotake
Mutou, Tsuyoshi
Hirano, Junko
Sakakura, Akira
Ogawa, Takeshi
Nisiwaki, Masanori
Yamada, Kiyoyuki
The C21-C34 segment 2 of aplyronine A (1), a potent antitumor substance of marine origin, was synthesized enantioselectivity in 25 steps (17% overall yield) from imide 11.
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