Synthetic studies on aplyronine A, a potent antitumor substance of marine origin: Stereocontrolled synthesis of the C21-C34 segment

DOI: 10.1016/0040-4039(94)88035-2

Source and publish data:

Tetrahedron Letters p. 1247 - 1250 (1994)

Update date:2022-08-05

Topics:

Authors:

Kigoshi, Hideo

Ojika, Makoto

Suenaga, Kiyotake

Mutou, Tsuyoshi

Hirano, Junko

Sakakura, Akira

Ogawa, Takeshi

Nisiwaki, Masanori

Yamada, Kiyoyuki

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Article abstract of DOI:10.1016/0040-4039(94)88035-2

The C21-C34 segment 2 of aplyronine A (1), a potent antitumor substance of marine origin, was synthesized enantioselectivity in 25 steps (17% overall yield) from imide 11.

Full text of DOI:10.1016/0040-4039(94)88035-2

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