Synthetic studies on aplyronine A, a potent antitumor substance of marine origin: Stereocontrolled synthesis of the C21-C34 segment

DOI: 10.1016/0040-4039(94)88035-2

Source and publish data:

Tetrahedron Letters p. 1247 - 1250 (1994)

Update date:2022-08-05

Topics:

Authors:

Kigoshi, Hideo

Ojika, Makoto

Suenaga, Kiyotake

Mutou, Tsuyoshi

Hirano, Junko

Sakakura, Akira

Ogawa, Takeshi

Nisiwaki, Masanori

Yamada, Kiyoyuki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(94)88035-2

The C21-C34 segment 2 of aplyronine A (1), a potent antitumor substance of marine origin, was synthesized enantioselectivity in 25 steps (17% overall yield) from imide 11.

Full text of DOI:10.1016/0040-4039(94)88035-2

Products guided by the article

Product name:(2R,3S)-5-Benzyloxy-2-methyl-3-triethylsilanyloxy-pentanoic acid methoxy-methyl-amide

Cas No:157220-40-1

R&D Labs maybe for 157220-40-1

NingBO Hong Xiang Biochem.Co.Ltd

website:http://www.hxbiochem.com

Contact:0574-66003444

Address:Ning Bo Bei Lun
LINYI FUDE FINE CHEMICAL CO.,LTD

Contact:86-539-2361184

Address:YISHUI, LINYI,SAHNDONG,CHINA
Chengdu Aslee Biopharmaceuticals, Inc

Contact:18608018419

Address:Chengdu Aslee Biopharmaceuticals, Inc
Hangzhou Mole's Science & Technology Co.,Ltd.(expird)

Contact:+86-571-56880228

Address:15F Guodu development Building, NO.182 Zhaohui Road
Li's chemicals

Contact:+86-15850770348

Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China

Relevant to this article

Semi-synthetic C23-substituted milbemycins via spiroacetal cleavage and resynthesis

Doi:10.1016/0040-4039(94)85226-X
(1994)
Arenes to Substituted Cyclohexadienes: Nucleophile/Electrophile Additions across an Arene Double Bond

Doi:10.1021/jo00096a019
(1994)
Doi:10.1016/S0040-4020(01)92780-2
(1970)
Ruthenium-catalyzed reduction of carbon dioxide to formaldehyde

Doi:10.1021/ja500708w
(2014)
Anion-induced dimerization in p-squaramidocalix[4]arene derivatives

Doi:10.1021/jo500422u
(2014)
Chiral Diaminodiamide Copper(II) Complexes for the Enantioselective Recognition of Amino Acids: Synthesis of the Ligands and Formation Constants

Doi:10.1002/hlca.19860690818
(1986)

Article Doi