Catalytic enantioselective macrolide synthesis II: Use of differential deprotection protocols

Article abstract of DOI:10.1016/0957-4166(94)80156-8

Catalytic enantioselective synthesis of Phorcantholide I has been achieved. Key stereochemistry was introduced using a chiral arene chromium tricarbonyl based catalyst to mediate the addition of dimethyl zinc to a functionalised aldehyde. During the synth