Syntheses of novel bicyclic β-lactams by intramolecular nucleophile transfer reactions of N-tosyloxy β-lactams

Article abstract of DOI:10.1016/S0040-4020(01)85552-6

Intramolecular nucleophile transfer reaction of several N-tosyloxy β- lactams was applied to construct a new six-membered ring in the product bicyclic β-lactams. The bicyclic products generally possessed cis stereochemistry on the β-lactam ring. The major