Synthesis of Chiral Diether and Tetraether Phospholipids: Regiospecific Ring Opening of Epoxy Alcohol Intermediates Derived from Asymmetric Epoxidation

DOI: 10.1021/jo00090a011

Source and publish data:

Journal of Organic Chemistry p. 2945 - 2955 (1994)

Update date:2022-08-05

Topics:

Authors:

Thompson, David H.

Svendsen, Chris B.

Meglio, Ciro Di

Anderson, Valerie C.

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Article abstract of DOI:10.1021/jo00090a011

Diether and tetraether phospholipids have been synthesized using chiral epoxy alcohol starting materials (e.g. glycidol 3-nitrobenzenesulfonate esters or tert-butyldiphenylsilyl ethers).These chiral precursors provide control over the stereochemistry, sub

Full text of DOI:10.1021/jo00090a011

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