Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists

DOI: 10.1016/S0960-894X(98)00654-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3577 - 3582 (1998)

Update date:2022-08-04

Topics:

Authors:

Chambers

Antognoli

Cheng Cheng

Kuperman

Liston Liston

Marfat Marfat

Owens Owens

Pillar Pillar

Shirley Shirley

Watson Watson

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Article abstract of DOI:10.1016/S0960-894X(98)00654-4

A new series of cysLT₁ receptor antagonists represented by CP-288,886 (7) and CP-265,298 (8) were developed which are equipotent to clinical cysLT₁ receptor antagonists Zafirlukast (1) and Pranlukast (2).

Full text of DOI:10.1016/S0960-894X(98)00654-4

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