A SHORT APPROACH TO FUNCTIONALISED HOMOCHIRAL PIPERIDINONES

DOI: 10.1016/0957-4166(94)80113-4

Source and publish data:

Tetrahedron Asymmetry p. 1463 - 1464 (1994)

Update date:2022-08-04

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Authors:

Hermitage, Stephen A.

Moloney, Mark G.

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Article abstract of DOI:10.1016/0957-4166(94)80113-4

The preparation of homochiral lactam 4 in 5 steps from (S)-lysine is described.Conversion to bicyclic O,N-acetal 5 provides a useful template for further elaboration to highly substituted piperidinones with excellent diastereoselectivity.

Full text of DOI:10.1016/0957-4166(94)80113-4

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