A novel entry into 1,2,3,4,5,6-hexahydro-3-benzazocine-4,6-dione and 2-substituted-2,5,6,7-tetrahydro-4-benzazonine-1,3-(4H)-dione

Article abstract of DOI:10.1016/S0040-4020(01)85382-5

2-substituted-1,2,3,4,5,6-hexahydro-3-benzazocine-4, 6-diones (1a-d) and 2-methoxy-2,5,6,7-tetrahydro-4-benzazonine-1,3-dione 8 were synthesized through an oxidative ring expansion reaction of 6-methylthio-7 substituted-benzo[a] octem (2a-d) and 7-methylt