Total Synthesis of the Polyene Macrolide Antibiotic Roxaticin. II. Total Synthesis of the Roxaticin

DOI: 10.1016/0040-4020(95)00215-T

Source and publish data:

Tetrahedron p. 5315 - 5330 (1995)

Update date:2022-08-04

Topics:

Authors:

Mori, Yuji

Asai, Motoya

Kawade, Jun-ichiro

Furukawa, Hiroshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00215-T

Roxaticin has been synthesized in a convergent manner from the polyol segment 2, which was prepared by the Julia coupling reaction of sulfone 4 and aldehyde 8, and the polyene phosphonate 3.The cyclization was achieved by macrolactonization.

Full text of DOI:10.1016/0040-4020(95)00215-T

Products guided by the article

Product name:Toluene-4-sulfonic acid (2S,3S)-3-hydroxy-2,4-dimethyl-pentyl ester

Cas No:158557-15-4

R&D Labs maybe for 158557-15-4

Hebei Think-Do Environment Co., Ltd

website:http://www.thinkdo-environment.com

Contact:0311-86510809-

Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Chongqing Shuangfeng Chemical Co.,Ltd

Contact:+86-23-49850156

Address:No.663,xuanhua Rd,yongchuan,chongqing,China
Jiangsu Cale New Material Co.ltd

Contact:+86-515-88334667/88203550

Address:Zhongshan 3rd Road, Coastal Chemical Industry Park, Yancheng, Jiangsu, China
UNION PHARMPRO CO.,LTD

Contact:18710867521(wechat)

Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China
MTT Pharma & Bio-technology Co.,Ltd(expird)

Contact:+86-21-58407925

Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China

Relevant to this article

Synthesis and biological screening of novel indolalkyl arenes targeting the serotonine Transporter

Doi:10.1002/ardp.201300321
(2014)
Assembling chiral salan-copper(II) complexes into a 2D-network with carboxylic acid functionalization

Doi:10.1016/j.inoche.2014.02.009
(2014)
Facile synthesis of indene and fluorene derivatives through AlCl₃-catalyzed cyclization of in situ formed iminium ions

Doi:10.1002/aoc.3863
(2017)
Synthesis of a glycopeptide with phytoalexin elicitor activity. I. Syntheses of a triglycosyl L-serine and a triglycosyl L-seryl-L-proline dipeptide

Doi:10.1016/0008-6215(94)84227-2
(1994)
Ammonium acetate as a catalyst and/or reactant in the reaction of dimedone, aromatic aldehyde, and malononitrile: synthesis of tetrahydrobenzo[b]pyrans and hexahydroquinolines

Doi:10.1007/s00706-016-1683-0
(2016)
Synthesis of a 2-deoxyglucosyl analogue of medermycin

Doi:10.1039/b103080a
(2001)

Article Doi