Journal of Heterocyclic Chemistry p. 707 - 710 (1994)
Update date:2022-08-03
Topics:
Ono
Katayama
Nisyiyama
Ogawa
A general synthesis of 5-unsubstituted benzyl pyrrole-2-carboxylates was developed based on the reaction of β-nitroacetates with benzyl isocyanoacetate. The advantage of this route over other pyrrole syntheses was the regiochemical control of the substitution pattern on the pyrrole ring.
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