Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase: A New Class of Antiviral Agents

DOI: 10.1021/jm00018a022

Source and publish data:

Journal of Medicinal Chemistry p. 3617 - 3623 (1995)

Update date:2022-08-03

Topics:

Authors:

Moss, Neil

Beaulieu, Pierre

Duceppe, Jean-Simon

Ferland, Jean-Marie

Gauthier, Jean

et al. et al.

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Article abstract of DOI:10.1021/jm00018a022

We have been investigating a new class of antiviral compounds effective against herpes simplex virus (HSV) in vitro and in vivo.Antiviral activity results from inhibition of HSV ribonucleotide reductase (RR).The inhibitors are designed as mimics of the RR

Full text of DOI:10.1021/jm00018a022

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