Development of Methods for the Synthesis of Chiral, Highly Functionalized 2-Amino-4-Aryl-4H-Pyrans

DOI: 10.1016/S0040-4020(01)87029-0

Source and publish data:

Tetrahedron p. 3509 - 3528 (1994)

Update date:2022-08-03

Topics: Synthesis Yield Chiral Catalyst Stereochemistry Functionalized Reaction Conditions

Authors:

Marco, Jose L.

Martin, Nazario

Martinez-Grau, Angeles

Seoane, Carlos

Albert, Armando

Cano, Felix H.

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Article abstract of DOI:10.1016/S0040-4020(01)87029-0

The development of new methods for the asymmetric synthesis of highly functionalized 2-amino-4-aryl-4H-pyrans is described.Two alternative synthetic routes: the 1,4-conjugate addition of chiral β-ketoesters 3 or the N-acetoacetyl sultam 11 to arylidenemal

Full text of DOI:10.1016/S0040-4020(01)87029-0

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