Cycloaddition chemistry of anhydro-4-hydroxy-1,3-thiazolium hydroxides (thioisomunchnones) for the synthesis of heterocycles

Article abstract of DOI:10.1055/s-1994-25621

A series of α,α-disubstituted thioisomunchnones were prepared by treating acyclic or cyclic thioamides with bromoacetyl chloride in the presence of triethylamine. The resulting mesoionic dipole was found to undergo bimolecular 1,3-dipolar cycloaddition wi