Helvetica Chimica Acta p. 631 - 644 (1994)
Update date:2022-08-05
Topics:
Van Calenbergh
Van Den Eeckhout
Herdewijn
De Bruyn
Verlinde
Hol
Callens
Van Aerschot
Rozenski
A series of 2'-benzamido-2'-deoxyadenosine analogues were synthesized in an effort to find new lead structures for the treatment of sleeping sickness. The 2'-deoxy-2'-(3-methoxybenzamido)adenosine (1h) was proved to be a selective inhibitor of the parasit
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