Synthesis of chiral succinates via Pd(0) catalyzed carbonylation/asymmetric hydrogenation sequence

DOI: 10.1016/S0040-4039(00)75976-4

Source and publish data:

Tetrahedron Letters p. 835 - 838 (1994)

Update date:2022-08-04

Topics:

Authors:

Freskos Freskos

Laneman Laneman

Reilly Reilly

Ripin Ripin

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Article abstract of DOI:10.1016/S0040-4039(00)75976-4

We report a novel 4 step synthesis of chiral trisubstituted succinic acid derivatives utilizing carbonylation of a vinyl triflate followed by catalytic asymmetric hydrogenation to yield the title compounds.

Full text of DOI:10.1016/S0040-4039(00)75976-4

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