Total Synthesis of Alternaric Acid

DOI: 10.1016/S0040-4039(00)77605-2

Source and publish data:

Tetrahedron Letters p. 2327 - 2330 (1993)

Update date:2022-07-30

Topics: Characterization functional group interconversions Biological testing Retrosynthetic analysis Stereochemistry Control Purification and Isolation Ring Formation Protection and Functional Group Manipulation Assembly of Fragments Late-Stage Modifications

Authors:

Tabuchi, Hiroyasu

Hamamoto, Taisuke

Miki, Shokyo

Tejima, Tsuyoshi

Ichihara, Akitami

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)77605-2

A total synthesis of alternaric acid (1) has been achieved.Key reactions include the Julia olefination of tertiary aldehyde 4 and phenylsulfone 5, and novel one-pot construction of 3-acyl-4-hydroxy-5,6-dihydropyrone via Fries type rearrangement of O-enola

Full text of DOI:10.1016/S0040-4039(00)77605-2

Products guided by the article

Product name:methyl 4-methylene-6-(phenylthio)hexanoate

Cas No:160189-64-0

R&D Labs maybe for 160189-64-0

shijiazhuang baisheng chem co.; ltd

Contact:86-0311-80790826

Address:shijiazhuang hebei
Yingkou Sanzheng New Technology Chemical Industry Co., Ltd.

Contact:+86-417-2927806

Address:yingkou
ShangHai BMG Chemical Co., Ltd

Contact:+86-13524845543

Address:Room 602, no 291 sikai road shanghai
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY

Contact:0086-0757-85609331

Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
Shanghai Demand Chemical Co., ltd，China

Contact:86-021-55237578/55239122

Address:Room 3H, No.578, Yingkou Road, Yangpu District, Shanghai, China

Relevant to this article

Time-dependent diaryl ether inhibitors of InhA: Structure-activity relationship studies of enzyme inhibition, antibacterial activity, and in vivo efficacy

Doi:10.1002/cmdc.201300429
(2014)
A mild hydration of nitriles into amides

Doi:10.1016/S0040-4039(00)76229-0
(1994)
Regio and Enantioselective Synthesis of 4-Carbomethoxymethyl-1,4 Dihydropyridines

Doi:10.1016/S0040-4039(00)73518-0
(1994)
Discovery of γ-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor α converting enzyme: Design, synthesis, and structure-activity relationships

Doi:10.1021/jm0255670
(2002)
New catalytic model systems of tyrosinase: Fine tuning of the reactivity with pyrazole-based N-donor ligands

Doi:10.1039/c3cc47888b
(2014)
The cytotoxic properties of some tricyclic 1,3-dithiolium flavonoids

Doi:10.3390/molecules24132459
(2019)

Article Doi