Regio and Enantioselective Synthesis of 4-Carbomethoxymethyl-1,4 Dihydropyridines

DOI: 10.1016/S0040-4039(00)73518-0

Source and publish data:

Tetrahedron Letters p. 5433 - 5436 (1994)

Update date:2022-07-30

Topics:

Authors:

Raussou, Sabine

Gosmini, Romain

Mangeney, Pierre

Alexakis, Alexandre

Commercon, Monique

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Article abstract of DOI:10.1016/S0040-4039(00)73518-0

Regio and enantioselective 1,4 addition of ethoxyvinyl copper reagent on a pyridine bearing in position 3 a chiral aminal is described.This reaction allows the synthesis of various chiral N-acyl-4-methoxymethyl-1,4-dihydropyridines.

Full text of DOI:10.1016/S0040-4039(00)73518-0

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Product name:[(S)-3-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-4-((Z)-2-ethoxy-vinyl)-4H-pyridin-1-yl]-phenyl-methanone

Cas No:160744-78-5

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