
Tetrahedron p. 11721 - 11728 (1994)
Update date:2022-08-04
Topics:
Hulst, Ron
Vries, N. Koen de
Feringa, Ben L.
Diastereomeric amide derivatives of chiral phosphorinane 8 and unprotected amino acids are easily prepared in aqueous solutions, showing well separated signals in the 31P NMR spectra allowing accurate enentiomeric excess determination.Moreover, the obtained diastereomeric shift dispersion appears to be highly pH dependent, indicating the influence of intramolecular ion pair formation on the diastereomeric shift dispersion.
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