Biologically active dihydrodiol metabolites of polycyclic aromatic hydrocarbons structurally related to the potent carcinogenic hydrocarbon 7,12-dimethylbenz[a]anthracene

DOI: 10.1021/jm00396a023

Source and publish data:

Journal of Medicinal Chemistry p. 154 - 159 (1988)

Update date:2022-08-05

Topics:

Authors:

Harvey Harvey

Cortez Cortez

Sugiyama

Ito Ito

Sawyer Sawyer

DiGiovanni

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Article abstract of DOI:10.1021/jm00396a023

Syntheses of the trans-dihydrodiol derivatives implicated as the proximate carcinogenic metabolites of the polycyclic hydrocarbons cholanthrene, 6-methylcholanthrene, benz[a]anthracene, and 7- and 12-methylbenz[a]anthracene are described. These compounds

Full text of DOI:10.1021/jm00396a023

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