Three-component reaction for the synthesis of diverse unsaturated α-amino esters

DOI: 10.1016/j.tet.2013.11.107

Source and publish data:

Tetrahedron p. 3243 - 3248 (2014)

Update date:2022-09-26

Topics:

Authors:

Stefani, Hélio A.

Manarin, Flávia

Sousa, Ariane C.S.

Souza, Frederico B.

Ferraz, Witor Ribeiro

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Article abstract of DOI:10.1016/j.tet.2013.11.107

We describe an efficient multicomponent reaction for the preparation of unsaturated α-amino esters by ytterbium triflate catalyzed reaction of potassium organotrifluoroborate salts, aniline and ethyl glyoxalate. The synthetic viability of this protocol wa

Full text of DOI:10.1016/j.tet.2013.11.107

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