Tetrahedron Letters p. 7525 - 7528 (1994)
Update date:2022-08-04
Topics:
Davis, Franklin A.
Zhou, Ping
A concise, highly efficient asymmetric synthesis of aminopropanediol (1R,2R)-(-)-3, precursor to the broad spectrum antibiotics thiamphenicol/florfenicol 1/2, was prepared in two steps from cis-aziridine 2-carboxylic acid (2S,3S)-(-)-5.
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