A Sequential Anionic Cycloaddition And Thermal Cycloreversion Strategy to Furocoumarins: A Concise Synthesis of Methoxsalen

DOI: 10.1016/0040-4039(94)88526-5

Source and publish data:

Tetrahedron Letters p. 9617 - 9618 (1994)

Update date:2022-08-02

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Authors:

Mal, Dipakranjan

Murty, Kadiyala V. S. N.

Datta, Kalyani

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Article abstract of DOI:10.1016/0040-4039(94)88526-5

The synthesis and utility of unprecedented fluorenofurans 7 and oxa-s-indacenones 8 as key intermediates for synthesis of methoxsalen 1 is described, illustrating a novel synthetic approach to furocoumarins.

Full text of DOI:10.1016/0040-4039(94)88526-5

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Product name:8-Methoxy-5-phenylsulfanyl-5,6-dihydro-indeno[5,6-b]furan-7-one

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