Synthesis of 3'-fluoro-3'-deoxy-N6-cyclopentyladenosine

Article abstract of DOI:10.1080/15257779408010677

Starting from 9-(β-D-xylofuranosyl)-6-chloropurine, the title compound was prepared in four steps. Reaction with cyclopentylamine followed by treatment of the 2'-O,5'-O-ditritylated material with diethylaminosulfur trifluoride (DAST), yielded after deprot

Full text of DOI:10.1080/15257779408010677

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Nucleosides and Nucleotides
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Synthesis of 3′-Fluoro-3′-deoxy-N6-
cyclopentyladenosine
G. Ceulemans a , R. Busson a , N. Weyns a , F. Vandendriessche a , J.
Rozenski a , A. IJzerman b & P. Herdewijn a
a Rega Institute for Medical Research, Laboratory of Medicinal
Chemistry, Katholieke Universiteit Leuven , B-3000, Leuven, Belgium
b Center for Bio-pharmaceutical Sciences, Division of Medicinal
Chemistry , Leiden University , 2300 RA, Leiden, The Netherlands
Published online: 24 Sep 2006.
To cite this article: G. Ceulemans , R. Busson , N. Weyns , F. Vandendriessche , J. Rozenski , A.
IJzerman & P. Herdewijn (1994) Synthesis of 3′-Fluoro-3′-deoxy-N6-cyclopentyladenosine, Nucleosides
and Nucleotides, 13:9, 1991-2000, DOI: 10.1080/15257779408010677
To link to this article: http://dx.doi.org/10.1080/15257779408010677
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