European Journal of Medicinal Chemistry p. 639 - 647 (1994)
Update date:2022-08-04
Topics:
Langlois
Quintard
Abalain
It is demonstrated that HIV-1 protease is essential for the assembly and infectivity of the acquired immunodeficiency syndrome (AIDS) virus. This protease is an aspartyl protease with a 2-fold symmetry axis. Potential inhibitors were synthesized and consi
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