Rearrangement of 2-(Arylmethoxy)methyl-2-oxazolines via Lithium Azaenolates: a Facile Synthetic Route to ortho-Methylmandelic Acid Derivatives

DOI: 10.1039/c39940002771

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 2771 - 2772 (1994)

Update date:2022-07-29

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Authors:

Kamata, Kazuyuki

Terashima, Masanao

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Article abstract of DOI:10.1039/c39940002771

2-(Arylmethoxy)methyl-2-oxazolines, on treatment with LDA in THF at low temperature, rearrange to afford products which are hydrolysed to ortho-methylmandelic acids or α-(1-methyl-2-naphthyl)glycolic acid.

Full text of DOI:10.1039/c39940002771

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