Journal of labelled compounds and radiopharmaceuticals p. 915 - 920 (1994)
Update date:2022-07-30
Topics: Purification and characterization Final steps Starting Materials Biological Studies Construction of the Quinoline Ring Additional Transformations
Kuo
Wheeler
The synthesis of the C-14 labeled isotopomer of LY300502, a potent 5α-reductase inhibitor has been accomplished in four radiochemical steps. The route involves the synthesis of LY300502-[14C] from LY300502 via a circuitous route; the label was introduced with ethyl chloroformate-[carbonyl-14C]
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