Synthesis p. 1401 - 1402 (1994)
Update date:2022-07-30
Topics:
Hocek
Masojidkova
Holy
A simple synthesis of 2-(aminomethyl)purines is reported. Imidate intermediates are formed by condensation of the Cb-glycine ortho-ester with 4-aminoimidazole-5-carboxylic acid derivatives, and are further cyclized to 2-(Cb-aminomethyl)purines.
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Doi:10.1016/0277-5387(94)00231-3
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(2014)Doi:10.1021/jo5011558
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