Advanced Synthesis and Catalysis p. 2203 - 2208 (2014)
Update date:2022-08-05
Topics:
J?rres, Manuel
Chen, Xia
Ace?a, José Luis
Merkens, Carina
Bolm, Carsten
Liu, Hong
Soloshonok, Vadim A.
A new multipurpose glycine equivalent for the general asymmetric synthesis of α-amino acids is introduced. The chiral reagent can be transformed to various amino acids by alkylations with alkyl halides as well as aldol and Michael addition reactions under operationally convenient reaction conditions at room temperature with virtually complete stereochemical control.
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Doi:10.1002/ejoc.201402192
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