A-aminopurine derivatives with C6-substituted olefin as novel cross-linking agents and the synthesis of the corresponding β-phosphoramidite precursors

DOI: 10.1016/S0040-4020(97)00069-0

Source and publish data:

Tetrahedron p. 3035 - 3044 (1997)

Update date:2022-08-04

Topics:

Authors:

Nagatsugi, Fumi

Uemura, Kengo

Nakashima, Shouji

Maeda, Minoru

Sasaki, Shigeki

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Article abstract of DOI:10.1016/S0040-4020(97)00069-0

The 6-vinylated 2-aminopurine nucleoside (1), which was prepared by the Pd(0)-catalyzed cross-coupling reaction using guanosine 6-O-tosylate and vinyltributylstannane, has been demonstrated as a potential cross-linking agent. However, attempts for its inc

Full text of DOI:10.1016/S0040-4020(97)00069-0

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