Synthesis and structure-activity relationships of some novel oxetane carbapenems

DOI: 10.1016/S0960-894X(97)00280-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1805 - 1810 (1997)

Update date:2022-08-03

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Authors:

Sakya, Subas M.

Strohmeyer, Timothy W.

Bitha, Panayota

Lang Jr., Stanley A.

Lin, Yang-I.

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Article abstract of DOI:10.1016/S0960-894X(97)00280-1

Six disubstituted oxetane carbapenems were synthesized and their antibacterial profile compared with the lead amino methyl THF carbapenem as well as imipenem. The oxetane carbapenems had comparable or less activity against the Gram(-) bacteria and had red

Full text of DOI:10.1016/S0960-894X(97)00280-1

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Product name:(2R,3R,4R)-3-Acetylsulfanyl-4-(toluene-4-sulfonyloxymethyl)-oxetane-2-carboxylic acid methyl ester

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