Synthesis of both enantiomers of dynemicin A model compound. New remote asymmetric induction in acetylide addition into quinoline nucleus as key step

Article abstract of DOI:10.1016/0040-4039(94)80032-4

A new and highly selective 1,4-asymmetric induction in the addition of magnesium acetylide into quinoline nucleus was developed. By using this reaction, both enantiomers of dynemicin A model compound were synthesized from chiral alcohol which was prepared