Tetrahedron p. 12853 - 12882 (1994)
Update date:2022-08-05
Topics:
Ishiwata, Hiroyuki
Sone, Hiroki
Kigoshi, Hideo
Yamada, Kiyoyuki
The total synthesis of doliculide (1), a potent cytotoxic cyclodepsipeptide from the Japanese sea hare Dolabella auricularia, has been achieved.The key step of the synthesis is the construction of the sereogenic centers of a 15-carbon polyketide-derived d
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