Synthesis and properties of 2-substituted 5-chloro-1,3-oxazole-4- carboxamides

Article abstract of DOI:10.1134/S1070363214060206

Chlorination of 2-aryl-5-benzylsulfanyl-1,3-oxazole-4-carbonitrile in aqueous acetic acid at 50-60°C afforded new 2-aryl-5-chloro-1,3-oxazole-4- carboxamides. The reactivity of the chlorine atom with respect to the N-, O-, and S-nucleophiles was investiga